ACCORD-CRC: Australian Comprehensive Cancer Outcomes and Research Database: COLORECTAL

Interventions: Data collected will include:
•Patient demographics and characteristics
•Disease clinicopathological and molecular features
•Treatment history
•Outcomes and survival
•Follow-up data at 3 to 6-montly intervals until death
There is no participant contact for clinical data collection as a waiver of consent is in place.
Participants will be asked to consent to any removed cancer samples being stored in tissue bank.
Primary outcome(s): Clinical data collection target of 10,000 colorectal cancer (CRC) patients as assessed by CRC registry data. This outcome is assessed by the use of statistical analytics software SAS to analyse the data and prepare regular reports on the target numbers.
[10 years]
Study Design: Purpose: Natural history;Duration: Longitudinal;Selection: Defined population;Timing: Both

干预措施：本次研究收集的数据包含以下内容：
• 患者人口统计学特征与临床基本特征
• 疾病的临床病理及分子生物学特征
• 治疗史
• 临床结局与生存情况
• 每3至6个月进行一次随访并收集随访数据，直至患者死亡

因已获批知情同意豁免，无需联系受试者开展临床数据采集工作。
将向受试者征求同意，将其切除的癌组织样本留存于组织库。

主要结局指标：本研究计划收集结直肠癌（colorectal cancer, CRC）患者临床数据共计10000例，该目标通过结直肠癌登记库数据进行评估。本结局指标将采用统计分析软件SAS（Statistical Analysis System）对数据进行分析，并定期针对目标入组数生成进度报告。
[研究周期：10年]

研究设计：研究目的为自然史研究；研究周期为纵向研究；入组人群为特定划定人群；数据采集时点采用双向采集方案。