Immunogenic peptides from APC mutations reported from different databases.
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https://figshare.com/articles/dataset/Immunogenic_peptides_from_APC_mutations_reported_from_different_databases_/7136789
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Immunogenic peptides were selected from a library of 9-mer peptides derived from non-synonymous single nucleotide variants and Indels resulting in amino acid alterations. The mutated peptides were selected on the basis of positive TCR binding and an HLA binding affinity of ≤500 nM. *OncoMD is MedGenome Labs’s proprietary database of somatic mutations. LOVD: Leiden Open (source) Variation Database UMD: Universal Mutation Database.
*免疫原性肽(immunogenic peptides)从由可引发氨基酸改变的非同义单核苷酸变异(non-synonymous single nucleotide variants)与插入缺失(Indels)所衍生的9聚体肽(9-mer peptides)库中筛选得到。本次筛选的突变肽以阳性T细胞受体(TCR)结合活性及≤500 nM的人类白细胞抗原(HLA)结合亲和力作为入选标准。*OncoMD为MedGenome实验室(MedGenome Labs)的专有体细胞突变数据库。LOVD:莱顿开放(源)变异数据库(Leiden Open (source) Variation Database);UMD:通用突变数据库(Universal Mutation Database)
创建时间:
2018-09-26



