Frequency of SCE and chromosome abnormalities

A Sister Chromatin Exchange (SCE) was scored each time a color switch between dark or light sister chromatids occurred, and chromosomal aberrations, including chromosomal breakage and fragmentation were analyzed was assessed as previously described [40]. NT- non-targeting.

每当明暗姐妹染色单体之间发生颜色转换时，即对姐妹染色单体交换（Sister Chromatid Exchange, SCE）进行评分；同时参照此前文献[40]所述方法，对包括染色体断裂与碎裂在内的染色体畸变进行分析与评估。NT-非靶向（non-targeting）。