Cryo-EM structure of SARS-CoV-2 nsp10-nsp14 (E191A) in complex with T20P14-S complex, monomeric form
收藏Protein Data Bank Japan2026-02-25 更新2026-03-21 收录
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Cryo-EM structure of SARS-CoV-2 nsp10-nsp14 (E191A) in complex with T20P14-S complex, monomeric form Descriptor: MAGNESIUM ION, Non-structural protein 10, Proofreading exoribonuclease, ... Authors: Yang, Y, Liu, C, Liu, B. Deposit date: 2025-10-16 Release date: 2026-01-28 Last modified: 2026-02-25 Method: ELECTRON MICROSCOPY (2.55 Å) Cite: Mechanism of SARS-CoV-2 resistance to nucleotide analog-based antivirals. Nat Commun, 17, 2026
严重急性呼吸综合征冠状病毒2(SARS-CoV-2)nsp10-nsp14(E191A)与T20P14-S复合物结合的单体形式冷冻电镜(Cryo-EM)结构
描述符:镁离子(MAGNESIUM ION)、非结构蛋白10(Non-structural protein 10)、校对型核糖核酸外切酶(Proofreading exoribonuclease)……
作者:Yang Y、Liu C、Liu B
沉积日期:2025-10-16
发布日期:2026-01-28
最后修改日期:2026-02-25
实验方法:电子显微镜(分辨率2.55埃)
引用文献:《SARS-CoV-2对基于核苷酸类似物的抗病毒药物的耐药机制》,《自然-通讯(Nat Commun)》,2026年,第17卷
创建时间:
2025-10-16



