Validation of the urgency questionnaire in Portuguese: A new instrument to assess overactive bladder syndrome

ABSTRACT Purpose Overactive Bladder (OAB) is a clinical condition characterized by symptoms reported by patients. Therefore, measurement instruments based on reported information are important for understanding its impact and treatment benefits. The aim of this study was to translate, culturally adapt and validate the Urgency Questionnaire (UQ) in Portuguese. Materials and Methods Initially, the UQ was translated and culturally adapted to Portuguese. Sixty-three volunteers were enrolled in the study and were interviewed for responding the Portuguese version of the UQ and the validated Portuguese version of the Overactive Bladder Questionnaire short-form (OABq-SF), used as the gold standard measurement for the validation process. Psychometric properties such as criterion validity, stability, and reliability were tested. Results Forty-six subjects were included in the symptomatic group (presence of “urgency”), and seventeen were included in the asymptomatic group (control group). There was difference between symptomatic and asymptomatic subjects on all of the subscales (p≤0.001). The UQ subscales correlated with the OABq-SF subscales (p≤0.01), except the subscale “time to control urgency” and the item “impact” from the visual analog scales (VAS). However, these scales correlated with the OABq-SF - Symptom Bother Scale. The UQ subscales demonstrated stability over time (p

摘要 研究目的 膀胱过度活动症（Overactive Bladder, OAB）是一类以患者自述症状为特征的临床病症，因此基于患者自述信息的评估工具对于了解该疾病的疾病负担与治疗获益具有重要意义。本研究旨在完成尿急问卷（Urgency Questionnaire, UQ）的葡萄牙语翻译、文化调适与效度验证工作。材料与方法 首先对尿急问卷进行葡萄牙语翻译与文化调适。本研究共纳入63名志愿者，对其进行访谈以使其填写葡萄牙语版尿急问卷，以及经验证的葡萄牙语版膀胱过度活动症简版问卷（Overactive Bladder Questionnaire short-form, OABq-SF）——该问卷作为本次验证流程的金标准评估工具。随后对该量表的心理测量学特性，包括效标效度、重测稳定性与信度等进行检验。结果 本研究共纳入症状组46例（存在尿急症状）与无症状对照组17例。症状组与无症状组在所有子量表上的得分均存在显著差异（p≤0.001）。尿急问卷各子量表与膀胱过度活动症简版问卷各子量表均呈显著相关（p≤0.01），仅“尿急控制时长”子量表与视觉模拟评分量表（Visual Analog Scales, VAS）中的“影响程度”条目除外。不过上述量表与膀胱过度活动症简版问卷的症状困扰量表呈显著相关。尿急问卷各子量表的重测稳定性良好（p