Implementation of Genomic Variant Calling Using GATK4, SPARK, WDL, CROMWELL and DOCKER Over Simulated Ebola NGS Dataset.

Genomic variant calling is automated using workflows written into WDL script. There are different scripts to execute genomic variant calling over non-SPARK, SPARK platform as well as DOCKER as runtime. Simulated ebola RNASEQ reads are used to benchmark the execution.

基因组变异检测（Genomic variant calling）通过集成于Workflow Description Language（WDL）脚本中的工作流实现自动化执行。针对非SPARK平台、SPARK平台以及以DOCKER作为运行时环境的各类场景，均配置了专属脚本以完成基因组变异检测任务。本数据集使用模拟的埃博拉病毒RNASEQ读段对上述工作流的执行性能进行基准测试。