Differentially represented proteins in response to tuberculosis identified by quantitative serum proteomics in Asian elephants

The study reported here is the first characterization of elephant serum proteome in response to TB. These results advance our understanding of elephant immune response to M. tuberculosis and provide potential biomarkers for diagnosis and control of TB in this endangered species.

本研究首次对感染结核病（TB）的大象血清蛋白质组（proteome）进行了表征分析。本研究结果深化了学界对大象针对结核分枝杆菌（M. tuberculosis）的免疫应答的认知，并为这一濒危物种的结核病诊断与防控提供了潜在生物标志物。