AA-1P

AA-1P investigates the impact of Lactobacillus paracasei treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection.The identification of the sample AA-1P:<br>A: Denotes the control group.<br>A: Represents timepoint 1, indicating sampling before C. difficile infection.<br>1: Refers to the specific mouse number under investigation.<br>P: Indicates the treatment administered, which in this case is Lactobacillus paracasei.

本研究（AA-1P队列）旨在探究副干酪乳杆菌（Lactobacillus paracasei）干预对艰难梭菌（Clostridioides difficile）感染小鼠肠道菌群的影响。研究收集感染后小鼠的粪便样本，采用Invitrogen试剂进行前处理，随后在Ion Torrent NGS系统上完成测序。通过Ion Reporter SW（16S）软件开展数据分析，结果显示感染后第1、3、6天，微生物类群的动态丰度发生显著改变，为阐明艰难梭菌感染期间益生菌调控肠道菌群的潜在潜力提供了重要见解。
样本AA-1P的命名规则如下：
A：代表对照组；
第二个A：代表时间点1，即艰难梭菌感染前的采样时间；
1：指代本次研究的特定小鼠编号；
P：代表所施加的干预措施，此处为副干酪乳杆菌处理。