A single cell transcriptomic atlas identifies synapse-associated microglia in the developing zebrafish (bulk cells)

This study profiles developing and adult zebrafish macrophages and defines regional and functional microglial subtypes. Macrophages (Mpeg+ and CD45+ cells) were sorted and sequenced from 28 dpf and 6 mpf zebrafish

本研究对发育阶段及成年斑马鱼的巨噬细胞进行了特征分析，并明确了具备区域分布特征与功能异质性的小胶质细胞亚型。研究从受精后28天（days post fertilization, dpf）及受精后6个月（months post fertilization, mpf）的斑马鱼体内分选得到巨噬细胞（Mpeg阳性与CD45阳性细胞）并完成了测序。