FK-8B

FK-8B investigates the impact of <i>Bifidobacterium</i> <i>bifidum</i> treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection.The identification of the sample FK-8B:<br>F: Denotes the strain ST-42 of Clostridioides difficile.<br>K: Represents timepoint 3, indicating sampling after treatment.<br>8: Refers to the specific mouse number under investigation.<br>B: Indicates the treatment administered, which in this case is <i>Bifidobacterium</i> <i>bifidum</i>.

FK-8B数据集旨在探究双歧双歧杆菌（Bifidobacterium bifidum）干预对艰难梭菌（Clostridioides difficile）感染小鼠肠道菌群的影响。研究人员对感染后的小鼠粪便样本采用Invitrogen相关流程进行处理，并于Ion Torrent下一代测序（NGS）系统上完成测序。通过Ion Reporter SW（16S）开展分析后，观察到感染后第1、3、6天的微生物类群动态发生显著变化，该结果为阐明艰难梭菌感染期间益生菌调控肠道菌群的潜在潜力提供了重要依据。
样本FK-8B的命名含义如下：
F：代表艰难梭菌菌株ST-42；
K：表示时间节点3，即给药后的采样时间点；
8：指代本次研究中的特定小鼠编号；
B：表示所施加的干预措施，本案例中为双歧双歧杆菌。