Transcriptome analysis of post-hatch breast muscle in legacy and modern broiler chickens reveals enrichment of several regulators of myogenic growth. Gallus gallus

We report the results of comparative transcriptional profiling in the pectoralis major muscle of a modern production broiler line (Ross 708) and a legacy broiler line inbred since the late 1940s (Illinois) focusing on metabolic differences and differences in myogenic growth regulators Overall design: Differential gene expression analysis between Ross 708 and Illinois pectoralis major at two post-hatch time points (D6 and D21) that bracket critical inflection point in the allometric growth characteristics of the muscle

本研究报道了现代商品肉鸡品系（Ross 708）与自20世纪40年代末起近交选育的经典肉鸡品系（Illinois）的胸大肌比较转录谱分析（comparative transcriptional profiling）结果，重点关注其代谢差异与肌源性生长调节因子（myogenic growth regulators）的表达差异。研究整体设计：在两个出壳后天数节点（孵化后第6天（D6）与第21天（D21））对上述两个品系肉鸡的胸大肌开展差异基因表达分析（differential gene expression analysis），这两个时间点覆盖了该肌肉异速生长（allometric growth）特性的关键拐点。