Rsk2 C-terminal Kinase Domain, (E)-tert-butyl 3-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-cyanoacrylate

Rsk2 C-terminal Kinase Domain, (E)-tert-butyl 3-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-cyanoacrylate Descriptor: Ribosomal protein S6 kinase alpha-3, SODIUM ION, tert-butyl (2S)-3-[4-amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-cyanopropanoate Authors: Serafimova, I.M, Pufall, M.A, Krishnan, S, Duda, K, Cohen, M.S, Maglathlin, R.L, McFarland, J.M, Miller, R.M, Frodin, M, Taunton, J. Deposit date: 2012-01-12 Release date: 2012-04-11 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles. Nat.Chem.Biol., 8, 2012

Rsk2 C端激酶结构域、(E)-3-(4-氨基-7-(3-羟丙基)-5-对甲苯基-7H-吡咯并[2,3-d]嘧啶-6-基)-2-氰基丙烯酸叔丁酯
描述项：核糖体蛋白S6激酶α-3、钠离子、(2S)-3-[4-氨基-7-(3-羟丙基)-5-(4-甲基苯基)-7H-吡咯并[2,3-d]嘧啶-6-基]-2-氰基丙酸叔丁酯
作者：Serafimova, I.M.、Pufall, M.A.、Krishnan, S.、Duda, K.、Cohen, M.S.、Maglathlin, R.L.、McFarland, J.M.、Miller, R.M.、Frodin, M.、Taunton, J.
存档日期：2012-01-12
发布日期：2012-04-11
最后修改日期：2024-10-09
实验方法：X射线衍射（分辨率2.4埃）
引用：《利用化学优化的亲电试剂可逆靶向非催化半胱氨酸》，《自然·化学生物学》（Nat.Chem.Biol.），第8卷，2012年