Significance of SNPs in CUGBP2 in prediction of disease risk.

aAllele depicted is the allele with higher frequency in the APOE ε4/ε4 cases than ε4/ε4 controls, as denoted on the Illumina TOP strand.bSample size.cP-value for relationship-corrected chi-square test of allele frequency differences.dInteraction odds ratio with respect to allele noted based on logistic regression model.eP-value for interaction coefficient of logistic model.

a. 本图所示等位基因为载脂蛋白E（APOE）ε4/ε4基因型病例组中频率高于同基因型对照组的等位基因，其标注基于Illumina TOP链（Illumina TOP strand）。
b. 样本量。
c. 针对等位基因频率差异的亲缘关系校正卡方检验对应的P值。
d. 基于逻辑回归模型计算得到的、与所标注等位基因相关的交互比值比（interaction odds ratio）。
e. 逻辑回归模型交互项系数对应的P值。