Alternatively activated macrophages. Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA85159
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Similar to asthma, nematode infections are commonly associated with production of Th2 cytokines and hyporesponsive T cells. This T cell phenotype has been reported to be induced by IL-4 dependent macrophages termed alternatively activated macrophages (AAM). Additionally, AAM have been implicated in several pulmonary diseases, including allergic asthma. This study examines the potential importance of AAM as immune regulatory cells in both infectious and noninfectious disease contexts. http://www.hopkins-genomics.org/asthma/asthma006/index.html Keywords: other
与哮喘相似,线虫感染常与Th2细胞因子(Th2 cytokines)的产生及低反应性T细胞(hyporesponsive T cells)的形成相关。据报道,这类T细胞表型可由被称为替代性活化巨噬细胞(alternatively activated macrophages,AAM)的白细胞介素4(IL-4)依赖性巨噬细胞诱导产生。此外,替代性活化巨噬细胞(AAM)还与包括过敏性哮喘在内的多种肺部疾病密切相关。本研究探讨了替代性活化巨噬细胞作为免疫调节细胞,在感染性与非感染性疾病情境中的潜在重要性。http://www.hopkins-genomics.org/asthma/asthma006/index.html 关键词:其他
创建时间:
2003-07-16



