Systematic analysis of tRNA-derived small RNAs in liver, spleen and small intestine of intrauterine growth retarded and normal pigs

tRFs (tRNA-derived small fragments) are a new class of small non-coding RNAs reported in recent years, with biological functions similar to microRNAs. In this study, we analysed the expression of tRFs in the liver, spleen and small intestine of intrauterine growth retarded (IUGR) and normal pigs using next-generation sequencing

tRNA衍生小片段（tRNA-derived small fragments，简称tRFs）是近年来报道的一类新型小型非编码RNA，其生物学功能与微小RNA（microRNAs）相似。本研究采用下一代测序（next-generation sequencing）技术，分析了宫内生长受限（intrauterine growth retarded，简称IUGR）猪与正常猪的肝脏、脾脏及小肠组织内tRFs的表达情况。