Screen mRNAs specifically regulated by mTORC1 in calvarial osteoblasts from mice

ChEBI2015-11-07 更新2026-07-12 收录

mTORC1信号通路

成骨细胞与软骨细胞基因表达谱

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-74781 数据链接链接失效反馈

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Screen mRNAs specifically regulated by mTORC1 in calvarial osteoblasts from mice

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2015-11-07

KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity

mTORC1信号通路

蛋白质修饰

Amino acids play crucial roles in the MTOR (mechanistic target of rapamycin kinase) complex 1 (MTORC1) pathway. However, the underlying mechanisms are not fully understood. Here, we establish a cell-f

DataCite Commons2025-01-27 更新80

Gene expression data from control and REPTOR (=CG13624) KO male adults

基因表达调控

mTORC1信号通路

The aim was to identify genes whose transcription is induced or repressed by REPTOR (=CG13624) KO in Drosophila melanogaster male adults. Data are part of the manuscript REPTOR and REPTOR-BP regulate

NIAID Data Ecosystem50

Activation of all three PPARs increased the expression of the peroxisomal genes Cat, Pex13 and Pex14.

PPARδ信号通路

成骨细胞与软骨细胞基因表达谱

Primary calvarial osteoblasts were treated with the indicated drugs and were analyzed for the Cat, Pex13 and Pex14 mRNA levels by qRT-PCR. Significant differences between the means ± SD (n = 4) of non

Figshare2015-12-08 更新30

Supplementary Material for: Distinct Gene Expression Patterns Defining Human Osteoblasts' Response to BMP2 Treatment: Is the Therapeutic Success All a Matter of Timing?

骨再生治疗响应预测

成骨细胞与软骨细胞基因表达谱

Background: Bone morphogenetic proteins (BMPs) play a key role in bone formation. Local application of BMP2 (Dibotermin alfa) supports bone formation when applied to complex fractures. However, up to

NIAID Data Ecosystem60

Nociceptor translational profiling reveals the RagA-mTORC1 network as a critical generator of neuropathic pain

神经病理性疼痛机制

mTORC1信号通路

Pain sensing neurons, nociceptors, are key drivers of neuropathic pain. We used translating ribosome affinity purification (trap) to comprehensively characterize up- and down-regulated mRNA translat

NIAID Data Ecosystem30

Screen mRNAs specifically regulated by mTORC1 in calvarial osteoblasts from mice

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