CHEK2 is recruited to DNA DSBs
收藏reactome.org2025-01-15 收录
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CHEK2 (CHK2, Cds1) is recruited to DNA double-strand breaks (DSBs) mainly through its interaction with TP53BP1 (53BP1) (Wang et al. 2002), but BRCA1 also contributes to CHEK2 recruitment (Wilson and Stern 2008).
CHEK2(CHK2,Cds1)主要通过与其相互作用(Wang et al. 2002)被招募至DNA双链断裂(DSBs),而BRCA1亦对CHEK2的招募起到一定的作用(Wilson and Stern 2008)。
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