Additional file 12 of Proteogenomic characterization of difficult-to-treat breast cancer with tumor cells enriched through laser microdissection

Additional file 12. Table S5. Differential biological pathways and functions between DTBC and LumA. (A) Genes and proteins that are significantly differentially expressed and share overlapping agreement in their upregulation (green) and downregulation (orange) between DTBC and LumA. (B) Genes that are significantly differentially expressed between DTBC and LumA and are linked to the IPA cell proliferation regulator network. The table concludes with the listing of 7 recognized IPA regulators, which are highlighted in yellow. (C) Proteins that are significantly differentially expressed between DTBC and LumA and are associated with the FOXC1 regulator network. (D) Predicted molecular functions by IPA for the differentially expressed phosphopeptides between DTBC and LumA.

补充材料12：表S5。DTBC与LumA之间的差异生物学通路及功能。(A) 在DTBC与LumA的比较中显著差异表达，且上调（以绿色标注）、下调（以橙色标注）的基因与蛋白质的表达变化具有重叠一致性；(B) 在DTBC与LumA间显著差异表达，且与Ingenuity通路分析（IPA）细胞增殖调控网络相关的基因，本表格末尾列出了7个经确认的IPA调控因子，以黄色高亮标注；(C) 在DTBC与LumA间显著差异表达，且与FOXC1调控网络相关的蛋白质；(D) IPA针对DTBC与LumA间差异表达的磷酸化肽段所预测的分子功能。