Representative TGFβ Related Genes expressed in Amela tumors and cultured cell lines.

(a)Genes known to be TGFβ responsive that show higher expression in Amela versus Mela primary tumors and are expressed at similar level in Amela primary tumors and in Amela lines in culture.
(b)Ratio of gene expression as log2 primary Amela/primary Mela > 1 with p values < 0.05;
*Ratio of gene expression as log2 primary Amela/primary Mela between 0 and 1 with p values < 0.05;
(c)Ratio of gene expression as Log2 (primary Amela/cultured Amela line) < 1 and/or with p value > 0.05 (ns). Log2 (primary Amela/cultured Amela line) < - 1 corresponds to higher expression in cultured Amela lines than in primary tumor.
(d)Numbered references can be found in Text S1.

(a) 已知为转化生长因子β（TGFβ）应答的基因，在Amela原发性肿瘤中的表达水平高于Mela原发性肿瘤，且在Amela原发性肿瘤与体外培养的Amela细胞系中表达水平相近。
(b) 基因表达比值（以log₂(原发性Amela/原发性Mela)计）大于1且P值小于0.05；
* 基因表达比值（以log₂(原发性Amela/原发性Mela)计）介于0至1之间且P值小于0.05；
(c) 基因表达比值（以log₂(原发性Amela/体外培养Amela细胞系)计）小于1，和/或P值大于0.05（无统计学意义，ns）。当log₂(原发性Amela/体外培养Amela细胞系)小于-1时，代表该基因在体外培养的Amela细胞系中的表达水平高于原发性肿瘤。
(d) 带编号的参考文献可参见补充文本S1（Text S1）。