Gene expression profiling of Dermal Papilla cells isolated from wild type (WT) and Fgfr1/Fgfr2 double mutant mice during anagen (at P14 and P16) was performed by RNA-seq analysis. Gene expression profiling of Dermal Papilla cells isolated from wild type (WT) and Fgfr1/Fgfr2 double mutant mice during anagen (at P14 and P16) was performed by RNA-seq analysis

Gene expression analysis revealed that the DP transcriptome is altered in the Fgfr1/Fgfr2 double mutant. At P14 the expression of 188 genes was significantly altered. At P16 the expression of 1082 genes were significantly altered. Overall design: 3 samples for wt and 3 samples for Fgfr1/Fgfr2 double mutant were used for each time point (P14 and P16)

基因表达分析显示，Fgfr1/Fgfr2双突变体中的DP转录组发生了改变。在出生后第14天（P14），共有188个基因的表达量出现显著差异；在出生后第16天（P16），共有1082个基因的表达量出现显著差异。实验整体设计：每个时间点（P14与P16）均设置3份野生型（wild type，缩写wt）样本与3份Fgfr1/Fgfr2双突变体样本。