A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies
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https://www.omicsdi.org/dataset/ecrin-mdr-crc/2389247
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资源简介:
* To evaluate the safety and tolerability of escalating doses of ERAS-007 in combination with other cancer therapies in study participants with advanced GI malignancies.
* To determine the Maximum Tolerated Dose (MTD) and/or Recommended Dose (RD) of ERAS-007 administered in combination with other cancer therapies.
* To evaluate the antitumor activity of ERAS-007 in combination with other cancer therapies.
* To evaluate the PK profiles of ERAS-007 and other cancer therapies when administered in combination.
* 评估ERAS-007递增剂量联合其他癌症疗法治疗晚期胃肠道(GI)恶性肿瘤受试者的安全性与耐受性。
* 确定ERAS-007联合其他癌症疗法给药的最大耐受剂量(Maximum Tolerated Dose, MTD)和/或推荐剂量(Recommended Dose, RD)。
* 评估ERAS-007联合其他癌症疗法的抗肿瘤活性。
* 评估ERAS-007与其他癌症疗法联合给药时的药代动力学(Pharmacokinetics, PK)特征。
创建时间:
2021-09-15



