Factors associated with adherence to pharmacological treatment among elderly persons using antihypertensive drugs

Abstract Objective: analyze adherence to pharmacotherapy and associated factors among elderly patients using at least one antihypertensive medication. Methods: A cross-sectional, population-based study was performed of elderly patients resident in Juiz de Fora, Minas Gerais, Brazil. Adherence to medication was assessed with the Morisky-Green Test. Socio-demographic variables and variables related to health status, the health service and drug therapy were collected. The Poisson regression model was used to assess crude and adjusted (95% confidence interval) prevalence ratios (PR). The level of significance was tested using the Wald test. Results: The prevalence of adherence to pharmacological therapy was 47% (95% CI: 41%-53%). The sample consisted of 279 elderly persons, the majority of whom were women (69%), described themselves as white (45.5%), and had up to four years of schooling (76.48%). Regarding pharmacological therapy, the subjects took 5.19 (±2.8) medications and 7.1 (±4.4) tablets per day. Conclusion: a significant association was observed between adherence to pharmacological therapy and the variables positive perception of vision, positive perception of hearing and absence of frailty.

### 摘要
#### 研究目的
分析至少服用1种降压药物的老年患者的药物治疗依从性及其相关影响因素。
#### 研究方法
本研究针对巴西米纳斯吉拉斯州茹伊斯迪福拉市的常住老年患者开展了一项横断面人群研究。采用莫里斯科-格林测试（Morisky-Green Test）评估患者的药物治疗依从性；收集受试者的社会人口学变量、健康状况相关变量、卫生服务相关变量及药物治疗相关变量。采用泊松回归模型计算粗患病率比与校正后患病率比（PR，95%置信区间），并通过瓦尔德检验（Wald test）进行显著性检验。
#### 研究结果
本研究中药物治疗依从率为47%（95%CI：41%~53%）。共纳入279名老年受试者，其中女性占比69%，自我报告为白人者占45.5%，受教育年限≤4年者占76.48%。在药物治疗方面，受试者平均服用5.19±2.8种药物，每日服药片数为7.1±4.4片。
#### 研究结论
本研究发现，药物治疗依从性与视力感知良好、听力感知良好以及无衰弱状态存在显著关联。