Compatibility: drugs and parenteral nutrition

ABSTRACT Objective Standardization and systematization of data to provide quick access to compatibility of leading injectable drugs used in hospitals for parenteral nutrition. Methods We selected 55 injectable drugs analyzed individually with two types of parenteral nutrition: 2-in-1 and 3-in-1. The following variables were considered: active ingredient, compatibility of drugs with the parenteral nutrition with or without lipids, and maximum drug concentration after dilution for the drugs compatible with parenteral nutrition. Drugs were classified as compatible, incompatible and untested. Results After analysis, relevant information to the product’s compatibility with parental nutrition was summarized in a table. Conclusion Systematization of compatibility data provided quick and easy access, and enabled standardizing pharmacists work.

摘要 目的：对数据进行标准化与系统化处理，以快速获取医院临床用于肠外营养（Parenteral Nutrition）的主流注射用药物的配伍相容性信息。方法：选取55种注射用药物，分别与二联型（2-in-1）及三联型（3-in-1）两种肠外营养制剂开展配伍分析。本次研究考量的变量包括：药物活性成分、药物与含/不含脂质肠外营养的配伍相容性，以及与肠外营养相容的药物经稀释后的最大药物浓度。最终将受试药物分为相容、不相容及未检测三类。结果：经分析后，将受试药物与肠外营养的配伍相关信息汇总为表格。结论：对配伍相容性数据进行系统化整理，实现了信息的快速便捷检索，同时可规范药师的临床工作流程。