Antimicrobial Resistance and Genomic Characteristics of Avian Pasteurella multocida

This study demonstrates the increasing prevalence of avian Pasteurella multocida in China, specifically the sustained circulation of ST129 and the recent emergence of ST471, particularly in ducks.These findings underscore the urgency of continuous monitoring of strain dissemination and the evolution of multidrug resistance, providing a scientific basis for precise and rational antimicrobials use in farms and for blocking the spread of potentially high-risk strains.

本研究证实，中国境内禽多杀性巴氏杆菌（avian Pasteurella multocida）的流行率呈持续上升趋势。具体而言，序列型129（Sequence Type 129，ST129）呈现持续循环传播的特征，而序列型471（Sequence Type 471，ST471）于近期出现，且该菌株的检出尤其集中于鸭群中。上述研究结果凸显了持续监测菌株传播与多重耐药性演化的紧迫性，可为养殖场精准合理使用抗菌药物以及阻断潜在高风险菌株的传播提供科学依据。