Characterization of serum small extracellular vesicles and their small RNA contents across human, rat, and mouse (data for rat and mouse)

In the present study, the isolated serum exosomes from healthy adults, rats, and mice were comparatively characterized; the small RNA compositions were analyzed; the serum exosome miRNA profiles and exosome depleted serum miRNA profiles were obtained by small RNAseq, and the distributions of miRNA component inside and outside of the serum exosomes were also compared.本研究对从健康成年人、大鼠及小鼠中分离得到的血清外泌体（exosomes）进行了比较性表征；对其小RNA组成展开分析；通过小RNA测序（small RNAseq）获取了血清外泌体miRNA谱与外泌体去除血清miRNA谱，并比较了miRNA组分在血清外泌体内外的分布特征。