Compounds with significant connections to the gene signature for letrozole treatment in breast cancer.

Those at the top of the table with positive setscores can elicit a transcriptional response similar to that of letrozole. At the bottom of the table with negative setscores are compounds that may elicit a transcriptional response opposite to that of letrozole. REF is the (drug) name for the reference set; TabNo () is the total number of gene signatures used in the perturbation analysis; SS is the total number of significant connections to REF from those signatures; PS is the perturbation stability , and SetNo is the setscore; SetS is the setsize.

表格中集合得分（setscore）为正的靠前化合物，可诱导出与来曲唑（letrozole）相似的转录应答反应。集合得分（setscore）为负的表格末尾化合物，则可诱导出与来曲唑相反的转录应答反应。REF为参考集的（药物）名称；TabNo为扰动分析中所用基因特征（gene signature）的总数量；SS为上述基因特征中与REF存在显著关联的总数量；PS为扰动稳定性；SetNo为集合得分（setscore）；SetS为集合大小（setsize）。