File S1 - Sputum Microbiota Associated with New, Recurrent and Treatment Failure Tuberculosis

Figure S1, Rarefaction analysis of 16S rRNA gene sequences of 3 groups of TB patients compared with healthy controls. F-TB, TB patients with treatment failure; HC, healthy controls; N-TB, new TB patients; R-TB, recurrent TB patients. Table S1, List of barcoded primers used in the study. Table S2, The existence of genera which were uniquely found in the sputum of TB patients. Table S3, OR and significance of existence of some specific microorganisms between TB patients and healthy controls. Table S4, Distribution of the most abundant genus in each group. Information S1, detailed figure legend in Figure 3b. (DOC)

补充图S1：3组结核病（Tuberculosis, TB）患者与健康对照的16S rRNA基因序列稀释曲线分析。其中F-TB为治疗失败结核病患者；HC为健康对照；N-TB为初治结核病患者；R-TB为复治结核病患者。补充表S1：本研究中使用的带条形码引物列表。补充表S2：仅在结核病患者痰液中特异性检出的菌属存在情况。补充表S3：结核病患者与健康对照间部分特定微生物存在情况的比值比（Odds Ratio, OR）及统计学显著性结果。补充表S4：各组中丰度最高菌属的分布情况。补充信息S1：图3b的详细图例（DOC格式文件）。