A summary of the dynamic analysis results of the T-LGL survival signaling network.

The first two columns from the left list the components of the network (except for the six source nodes) and their T-LGL states. The nodes' states marked with a * symbol were not documented experimentally in T-LGL before and were predicted by our steady state analysis. The references for the nodes' states documented before are given in the third column. The fixed point(s) obtained after each of the nodes' states is reversed is given in the fourth column, while the size of the exclusive basin of attraction of the normal fixed point, expressed as a percentage of the whole relevant state space, is indicated in the fifth column. The reference of the perturbation cases for which experimental evidence exists is given in the last column. The first 19 nodes in the first column are potential therapeutic targets for T-LGL leukemia.
1Evidence in NK-LGL leukemia.

从左侧数前两列，依次列出了该网络的各组分（六个源节点除外）及其T细胞大颗粒淋巴细胞白血病（T-LGL）状态。带有*标记的节点状态此前尚未在T-LGL相关研究中经实验记录，而是通过本研究的稳态分析预测所得。第三列列出了此前已被实验记录的节点状态的相关参考文献。第四列列出了逐个反转各节点状态后得到的不动点；第五列则以整体相关状态空间的百分比形式，标注了正常不动点的专属吸引域的大小。最后一列给出了存在实验证据支持的扰动案例的相关参考文献。第一列中的前19个节点是T-LGL白血病的潜在治疗靶点。
1 NK-LGL白血病相关证据。