Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=7ecb36b5dde8cd9d9e59c18cdd377f26
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资源简介：
We established a platform for the brain organoid culture by using human decellularized brain extracellular matrix (BEM) and a microfluidic device. This engineering concept of reconstituting brain-mimetic microenvironments facilitates development of a reliable culture platform for brain organoids, enabling effective modeling and drug development.
本研究采用人类脱细胞脑组织外基质（BEM）与微流控装置，构建了脑类器官培养平台。这一重构仿脑微环境的工程化策略，有助于打造可靠的脑类器官培养体系，可有效支撑脑疾病建模与药物研发。
提供机构：
Yonsei university
创建时间：
2022-02-20
