SynGeNet: Synergy from gene expression and network mining

SynGeNet R package implements a drug combination prediction method based on user-provided disease network data, drug target data and drug gene expression data. <br>Users have the option to provide their own disease network files or build disease networks using SynGeNet from a set of user-provided disease genes and gene expression fold-change data. Users are provided with a set of drug combination predictions ranked according to a synergy score.<br>Instructions for installation and demo data are provided in the R package.

SynGeNet R包实现了一种基于用户提供的疾病网络数据、药物靶点数据及药物基因表达数据的药物组合预测方法。
用户可自行提供疾病网络文件，也可借助SynGeNet，基于自身提供的疾病基因集与基因表达倍数变化数据构建疾病网络。
最终将输出一组按协同评分排序的药物组合预测结果。
该R包中附带了安装指南与演示数据集。