CRC100K (100,000 histological images of human colorectal cancer and healthy tissue)

这是一组 100,000 个非重叠图像块，来自人类结肠直肠癌 (CRC) 和正常组织的苏木精和伊红 (H&E) 染色组织学图像。
所有图像均为 224x224 像素 (px)，每像素 0.5 微米 (MPP)。
用于组织分类；类别是：脂肪（ADI），背景（BACK），碎片（DEB），淋巴细胞（LYM），粘液（MUC），平滑肌（MUS），正常结肠粘膜（NORM），癌症相关基质（STR），结直肠腺癌上皮（TUM）。
这些图像是从 NCT 生物库（德国海德堡国家肿瘤疾病中心）和 UMM 病理档案（大学医学中心）的福尔马林固定石蜡包埋 (FFPE) 样本中手动提取的 N=86 H&E 染色的人类癌症组织切片曼海姆，曼海姆，德国）。组织样本包含 CRC 原发性肿瘤切片和来自 CRC 肝转移灶的肿瘤组织；胃切除标本中的非肿瘤区域增加了正常组织类别，以增加变异性。

This dataset contains 100,000 non-overlapping image patches extracted from hematoxylin and eosin (H&E) stained histology images of human colorectal cancer (CRC) and normal tissues.
All images have a fixed size of 224×224 pixels (px) and a spatial resolution of 0.5 micrometers per pixel (MPP).
This resource is designed for tissue classification tasks, with the following category set: adipose (ADI), background (BACK), debris (DEB), lymphocytes (LYM), mucus (MUC), smooth muscle (MUS), normal colonic mucosa (NORM), cancer-associated stroma (STR), and colorectal adenocarcinoma epithelium (TUM).
These image patches were manually isolated from 86 H&E-stained human cancer tissue slides (N=86) obtained from formalin-fixed paraffin-embedded (FFPE) samples in the NCT Biobank (National Center for Tumor Diseases, Heidelberg, Germany) and the UMM Pathology Archives (University Medical Center Mannheim, Mannheim, Germany). The tissue samples include primary CRC tumor sections and tumor tissues from CRC liver metastases; non-tumor regions from gastrectomy specimens were added to the normal tissue category to increase the dataset's variability.