Protein networks are influenced by maternal BMI and differentiate preterm birth types

We conducted a study on a prospectively enrolled cohort in which we analyzed blood from pregnant women in the second trimester of pregnancy to look at thousands of proteins that might differ between those who delivered early and those who delivered full term. We discover distinct protein patterns for preterm birth types and find that body mass index strongly influences these patterns. These findings may help identify women at higher risk earlier in pregnancy and guide more personalized care and prevention strategies.