In-Office Tooth Bleaching for Adolescents Using Hydrogen Peroxide-Based Gels: Clinical Trial

Abstract The aim of the present study was to evaluate colorimetric changes and tooth sensitivity in adolescents and young patients submitted to tooth bleaching with 20% and 35% hydrogen peroxide. A randomized, controlled, clinical trial was conducted with 53 patients aged 11 to 24 years who were allocated to groups based on the use of the following commercial products: Whiteness HP - FGM® (35% hydrogen peroxide); Whiteness HP Blue Calcium - FGM® (35% hydrogen peroxide); and Whiteness HP Blue Calcium - FGM® (20% hydrogen peroxide). After the bleaching procedure, the visual analog scale was used to measure tooth sensitivity and the Vita Classical Shade guide was used to determine changes in tooth color. Statistical analysis involved the Friedman, Kruskal-Wallis and Student-Newman-Keuls tests, with p≤0.05 considered indicative of statistical significance. The addition of calcium contributed to a reduction in tooth sensitivity, especially when the lower concentration of hydrogen peroxide (20%) was used. Tooth sensitivity occurred in a transitory way and did not influence the tooth bleaching process. Significant differences in color were found after each of the two bleaching sessions. In-office tooth bleaching was considered an effective method for adolescents and young adults. Further studies in this population are necessary in order to fully evaluate the effects of bleaching in young teeth.

摘要 本研究旨在评估接受20%与35%过氧化氢牙齿漂白治疗的青少年及年轻患者的色度变化与牙齿敏感状况。本研究采用随机对照临床试验设计，纳入53名年龄介于11至24岁的受试者，依据所使用的商用漂白产品分为三组：Whiteness HP - FGM®（含35%过氧化氢）、Whiteness HP Blue Calcium - FGM®（含35%过氧化氢）以及Whiteness HP Blue Calcium - FGM®（含20%过氧化氢）。漂白操作完成后，采用视觉模拟量表（Visual Analog Scale）评估牙齿敏感程度，使用Vita经典比色板（Vita Classical Shade guide）测定牙齿色度变化。统计学分析采用Friedman检验、Kruskal-Wallis检验及Student-Newman-Keuls检验，以p≤0.05作为统计学显著性判定标准。添加钙成分可有效减轻牙齿敏感症状，尤其在使用较低浓度（20%）过氧化氢时效果更为显著。牙齿敏感呈一过性表现，未对牙齿漂白流程造成不良影响。两次漂白疗程后，牙齿色度均出现具有统计学意义的差异。诊室内牙齿漂白被认为是针对青少年及年轻成年人的有效美白手段。未来仍需针对该人群开展进一步研究，以全面评估牙齿漂白对年轻恒牙的作用效果。