RNA-seq analysis in triple negative breast cancer cells after knocking down DDX18. RNA-seq analysis in triple negative breast cancer cells after knocking down DDX18

To assess the function of DDX18 in TNBCs, we performed transcriptome analysis through high-throughput RNA-Seq of control and DDX18 knockdown cells Overall design: We knocked down DDX18 in MDA-MB-231 cells and performed the RNA-seq analysis in order to exam the transcriptome after DDX18 knockdown

为探究DDX18在三阴性乳腺癌（Triple-Negative Breast Cancer, TNBC）中的功能，我们通过对对照组及DDX18敲低细胞进行高通量RNA测序（RNA-Seq），开展了转录组分析。整体实验设计：我们在MDA-MB-231细胞中敲低DDX18，并进行RNA-seq分析，以检测DDX18敲低后的细胞转录组。