The RPE transcriptional response to light damage. Mus musculus

Transcriptional profiles were compared between dark adapted and light damaged BALBc (albino) mouse RPE. Keywords: stress response Overall design: BALBc mice were dark adapted for one week. To produce light damage a subset of the mice were then exposed to 6,000 lux white fluorescent light for 1.5 hours. RPEs were collected for RNA extraction 24 hours after light damage.

本研究对暗适应与光损伤后的BALB/c（白化）小鼠视网膜色素上皮（Retinal Pigment Epithelium, RPE）的转录组谱进行了比较。
关键词：应激反应
实验设计：BALB/c小鼠先进行为期一周的暗适应。为制备光损伤模型，将其中部分小鼠置于6000勒克斯（lux）白色荧光灯下照射1.5小时。光损伤24小时后，收集视网膜色素上皮组织用于RNA提取。