首页/数据集/Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment at developmental loci in ES cells

Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment at developmental loci in ES cells

ChEBI2013-09-30 更新2026-07-21 收录

组蛋白变体

细胞表观遗传调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-42155 数据链接链接失效反馈

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Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment at developmental loci in ES cells

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创建时间：

2013-09-30

组蛋白变体

染色质转录调控

Eukaryotic nucleosomes consists of an (H3-H4)2 tetramer and two H2A-H2B dimers, around which 147 bp of DNA are wrapped in 1.7 left-handed helical turns. During chromatin assembly, the (H3-H4)2 tetrame

Figshare2016-01-15 更新70

Epigenetic and chromatin profiling of wild-type and Dnmt3a-deficient B1 and B2 B cells. (CUT&RUN)

细胞表观遗传调控

B细胞发育分子机制

We have comprehensively interrogated wild type B1 and B2 B lineage cells and their progenitors. In mice bearing a conditional deletion of Dnmt3a in the B lineage, we integrated a variety of whole-geno

NIAID Data Ecosystem70

Complete RIP-seq g:Profiler results.

RNA-蛋白质互作组学

细胞表观遗传调控

DND1 is essential to maintain germ cell identity. Loss of Dnd1 function results in germ cell differentiation to teratomas in some inbred strains of mice or to somatic fates in zebrafish. Using our kno

Figshare2023-03-01 更新60

BRPF1 co-occupies with H3K4me3 and H3K23ac in human ESCs essential to pluripotency [ATAC-seq]

细胞表观遗传调控

组蛋白修饰互作

Post-translational modifications (PTMs) on histones play essential roles in cell fate decisions during development. However, how these PTMs are recognized and coordinated remains to be fully illuminat

NIAID Data Ecosystem70

Histone H1 binding is restricted by histone variant H3.3 (FAIRE). Drosophila melanogaster

染色质结构

组蛋白变体

Linker histones are involved in the formation of higher-order chromatin structure. Although linker histones have been implicated in the regulation of specific genes, it still remains unclear what thei

NIAID Data Ecosystem70

Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment at developmental loci in ES cells

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