Genomic Plasticity in Natural Populations of Bordetella pertussis

We determined the genomic organization of 14 clinical strains of Bordetella pertussis isolated over an 18-month period in Alberta, Canada. The maps of these 14 strains, while demonstrating general similarity of gene order, display a number of examples of genomic rearrangements in the form of large chromosomal inversions.

本研究解析了加拿大阿尔伯塔省18个月周期内分离获得的14株临床百日咳博德特菌（Bordetella pertussis）的基因组组织结构。上述14株菌株的基因组图谱虽在基因排列顺序上总体相似，但存在多例以大型染色体倒位为形式的基因组重排事件。