BAG for Signal transduction, DNA repair, marine & structural glycobiology, bacterial polyketide synthases, starch biosynthesis, regulation o
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https://doi.esrf.fr/10.15151/ESRF-ES-2006254164
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资源简介:
BAG regrouping small crystallographic teams at Lille, Orléans, Roscoff, Nancy and Marseille. For all projects both SAXS and MX-crystallography studies are
required to cover different aspects and scales of these often multimodular proteins. The projects in Lille concern Type V secretion systems, Sars-Cov proteins,
regulatory networks of signal transduction, starch metabolism (synthesis) and structural glycobiology. In Roscoff the projects concern marine glycobiology
and marine phage proteins, deciphering functions of 'unknown' proteins and PUL assemblages. The projects treated in Orléans are DNA structure and repair,
transcription regulation, molecular mechanisms of oxidative stress; in Nancy the studies concern the regulation and mechanisms of prokaryotic polyketide
syntheses. The subjects of Marseille are SAXS studies of ordered and disordered proteins involved in regulation of CO2 assimilation in microalgae.
BAG整合了里尔、奥尔良、罗斯科夫、南锡和马赛等地的小型晶体学团队。所有项目均需结合小角X射线散射(SAXS)和大分子X射线晶体学(MX-crystallography)研究,以覆盖这些多模块蛋白质在不同层面和尺度上的特性。里尔的项目涉及V型分泌系统、新冠病毒(Sars-Cov)蛋白、信号转导调控网络、淀粉代谢(合成)及结构糖生物学。罗斯科夫的项目聚焦海洋糖生物学与海洋噬菌体蛋白,旨在解析“未知”蛋白及多糖利用位点(PUL)组装体的功能。奥尔良的项目包括DNA结构与修复、转录调控、氧化应激的分子机制;南锡的研究则关注原核生物聚酮合成的调控及机制。马赛的研究主题为微藻中参与二氧化碳同化调控的有序及无序蛋白的SAXS研究。
提供机构:
European Synchrotron Radiation Facility
创建时间:
2025-02-07



