Direct Thioamination of Arynes via Reaction with Sulfilimines and Migratory N‑Arylation

A novel method for preparing a diverse range of o-sulfanylanilines is described. Direct thioamination of arynes with sulfilimines gives o-sulfanylanilines, involving C–N and C–S bond formations and migratory N-arylation.

本研究报道了一种可制备多样化邻巯基苯胺（o-sulfanylanilines）的新型合成方法。以芳炔（arynes）与硫亚胺（sulfilimines）为底物进行直接硫胺化反应，即可得到邻巯基苯胺，该过程涉及C–N键与C–S键的构建以及迁移N-芳基化反应。