Limitations in functioning in climacteric syndrome: a systematic literature review using the ICF

This study is the first of four preparatory studies in the process to develop an International Classification of Functioning, Disability and Health (ICF) Core Set for climacteric syndrome. The aim was to identify perimenopausal and postmenopausal limitations in functioning reported in the scientific literature. A systematic literature review was performed on MEDLINE, PsycInfo, Embase and CINAHL including publications from 2010 to 2020. Meaningful concepts were identified from the included studies and linked to the ICF using standardized linking rules. From the 6935 unique publications found, 300 articles were randomly selected for abstract screening and 48 studies met the inclusion criteria. From these, 1836 meaningful concepts were identified and linked to 158 different ICF categories. Most of them could be linked to the ICF chapter ‘Body Functions’. Emotional, sleep, energy and drive as well as thermoregulatory functions and sensation of pain were addressed in >80% of all publications. Climacteric syndrome involves all four components of the ICF, but the focus of scientific research lies on limitations in body functioning. Limitations in body structures, activities and participation and environmental factors were less frequently assessed. The ICF is a valuable tool to describe the multidimensional phenotype of climacteric syndrome.

本研究为制定围绝经期综合征（climacteric syndrome）的国际功能、残疾和健康分类（International Classification of Functioning, Disability and Health，以下简称ICF）核心套装流程中的四项预备研究之首。本研究旨在梳理科学文献中报道的围绝经期与绝经后人群的功能受限情况。研究团队针对MEDLINE、PsycInfo、Embase及CINAHL四大数据库开展系统文献综述，纳入2010至2020年发表的相关文献。从纳入的研究中提取有效概念，并依据标准化关联规则将其与ICF进行关联。在检索得到的6935篇非重复文献中，随机选取300篇进行摘要筛查，最终有48项研究符合纳入标准。从这48项研究中共提取1836个有效概念，并将其关联至158个不同的ICF类目。其中大部分概念可关联至ICF的“身体功能”章节。超80%的文献均提及了情绪、睡眠、精力与动力、体温调节功能以及痛觉感知等维度。围绝经期综合征涉及ICF的全部四大组成部分，但现有科学研究的焦点主要集中于身体功能受限方面。针对身体结构、活动与参与以及环境因素的受限情况，相关研究的评估频率则相对较低。ICF是描述围绝经期综合征多维表型的有效工具。