nuMoM2b Maternal Interview Visit 1 [V1A] Dataset in Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be

Data from Maternal Interview Visit 1 [V1A] form completed for all participants during the first study visit (6-13 weeks estimated gestational age), capturing information on the current pregnancy, medical history, reproductive history, social, demographic, and background information, alcohol consumption, smoking, and drug use, perceived stress scale, and physical activity
Study Description
NuMoM2b studied underlying, interrelated, mechanisms of adverse pregnancy outcomes (e.g., preterm birth, preeclampsia, fetal growth restriction) in pregnant women with no previous pregnancy lasting 20 weeks-0 days or more estimated gestational age (nulliparas). The network included 8 clinical sites, subsites, NICHD, and a data center. Women enrolled early in pregnancy and were followed through delivery, with study visits at 6 weeks-0 days to 13 weeks-6 days, 16 weeks-0 days to 21 weeks-6 days, 22 weeks-0 days to 29 weeks-6 days gestation, and delivery. Data collected through interviews, self-administered questionnaires, clinical measurements, ultrasounds, and medical records review included demographic, psychosocial, dietary, physiologic, health, and pregnancy outcome information. Subsets of participants enrolled in sleep disordered breathing, sleep patterns and quality, and fetal adrenal gland substudies. Pregnant women with no previous pregnancy lasting =20 weeks estimated gestational age (nulliparas); although 10,038 women enrolled in the study, during consent, only 9,289 of these women agreed to release their data into shared databases maintained by NIH

所有受试者在首次研究访视（估算孕周6~13周）时填写的产妇首次访视访谈[V1A]问卷数据，涵盖当前妊娠状况、既往病史、生育史、社会人口学特征与背景信息、饮酒、吸烟及药物使用情况、感知压力量表得分，以及身体活动相关信息。

研究概况
NuMoM2b研究针对无既往妊娠达到或超过20周0天估算孕周的孕妇（即初产妇），探索不良妊娠结局（如早产、子痫前期、胎儿生长受限）的潜在相互关联发病机制。本研究网络包含8个临床站点、亚站点、美国国立儿童健康与人类发育研究所（NICHD）以及1个数据中心。受试者于妊娠早期入组，随访至分娩完成，访视时间节点分别为：妊娠6周0天~13周6天、16周0天~21周6天、22周0天~29周6天，以及分娩时。研究通过访谈、自填式问卷、临床测量、超声检查及病历审查等方式收集数据，内容涵盖人口学特征、社会心理状况、膳食摄入、生理指标、健康状况及妊娠结局相关信息。部分受试者参与了睡眠呼吸障碍、睡眠模式与质量以及胎儿肾上腺亚研究。
本研究纳入无既往妊娠达到或超过20周估算孕周的孕妇（初产妇）；尽管共有10038名女性入组该研究，但在知情同意阶段仅9289名女性同意将其数据上传至由美国国立卫生研究院（NIH）维护的共享数据库中。