Study of the consistency, comparability and identity of different Dendritic cells productions for clinical use. Homo sapiens

Gene expression profiling of monocyte-derived Dendritic cells manufactured several times from one healthy donor and one single time from 8 different healthy donors to test the sources of variability Sources tested: Assay-related variability (8 samples), Manufacture-related variability (5 samples), Intra-donor-related variability (5 samples), inter-donor-related variability (9 samples) Overall design: 4 different levels of variability were accounted: Assay, manufacture, intradonor, and interdonor

本数据集针对单核细胞衍生树突状细胞（monocyte-derived Dendritic cells）开展基因表达谱分析，旨在探究实验变异性的来源。所用样本包括：1名健康供体的多次独立制备样本，以及8名不同健康供体的单次独立制备样本。本次测试的变异性来源分为四类：实验相关变异性（8份样本）、制备相关变异性（5份样本）、供体内变异性（5份样本）及供体间变异性（9份样本）。实验设计概述：本研究涵盖4类变异性维度，即实验、制备、供体内及供体间变异性。