Adult hippocampal neurogenesis in aged macaques and humans

We performed snRNA-seq of macaque hippocampal formation sample to investigate whether there is the existence of adult neural stem cells and adult hippocampal neurogenesis. Overall design: Single-nucleus RNA-seq for 3 macaque hippocampus (4, 11 and 23 years old) and 4 human hippocampus (67, 85, 87 and 92 years old) samples

本研究对猕猴海马结构样本开展单细胞核RNA测序（single-nucleus RNA sequencing, snRNA-seq），旨在探究成体神经干细胞与成体海马神经发生是否存在。整体实验设计：对3份猕猴海马样本（分别取自4、11、23岁个体）与4份人类海马样本（分别取自67、85、87、92岁个体）进行单细胞核RNA测序。