MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network with PRC2 [iCLIP]

We performed iCLIP for AGO2 to identify AGO2-interacting mRNAs in T98G glioblastoma multiforme cells. Overall design: iCLIP for AGO2.

我们在T98G多形性胶质母细胞瘤细胞中针对AGO2蛋白开展了单核苷酸分辨率紫外线交联免疫沉淀测序（iCLIP）实验，以鉴定与AGO2相互作用的信使RNA（mRNA）。实验整体设计：针对AGO2的iCLIP实验。