BHB/ketogenic diet_arthropathy_rat

We hypothesized that elevation of blood BHB concentrations could be effective for reducing the progression of bleeding-induced arthropathy by moderating the inflammatory responses of macrophages. In this study, we investigated whether BHB alleviates the arthropathy caused by repeated intra-articular blood injection in rats.

本研究提出如下假说：血液中BHB（β-羟基丁酸，β-Hydroxybutyrate）浓度升高，可通过调控巨噬细胞的炎症应答，有效延缓出血诱导性关节病的进展。本研究旨在探究BHB是否能够缓解大鼠反复关节腔内血液注射所引发的关节病。