Dataset on metabolic changes in different intestinal segments of type 1 diabetic mice

Type 1 diabetes (T1D) has been reported to cause systematic metabolic disorders, but metabolic changes in different intestinal segments of T1D remain unclear. Herein we analyzed metabolic profiles in the jejunum, ileum, cecum and colon of streptozocin-induced T1D and age-matched control (CON) mice by a LC-MS-based metabolomics method.

1型糖尿病（Type 1 diabetes, T1D）已被报道可引发系统性代谢紊乱，但目前1型糖尿病不同肠道节段的代谢变化仍不明确。本研究采用基于液相色谱-质谱（LC-MS）的代谢组学方法，分析了链脲佐菌素诱导的1型糖尿病小鼠及年龄匹配的对照（CON）小鼠的空肠、回肠、盲肠和结肠的代谢谱。