Abnormal histological findings - Female, 49 - Tissue image [6090730014738971]

This is the histopathological image of CERVIX UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 49Clinical description: Cervical dysplasia, HSILGender: FemaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter XVIII - Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedDiagnosis: Abnormal histological findingsResult of the histopathological examination: Foci of high-grade dysplasia (HSIL / CIN III), located near the transformation zone - IHC: p16 + (block reaction), increased Ki67 index,
present throughout the full thickness of the epithelium. Dysplastic changes do not reach the surgical margin of the endocervix. Features of mature and immature squamous metaplasia and a moderate chronic inflammatory infiltrate.Sample:Material: FFPECollecting method: Surgical specimenTopography: FEMALE GENITAL ORGANSOrgan: CERVIX UTERITissue: ExocervixType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk

这是格但斯克医科大学（Medical University Gdańsk）获取并存放于ZMDL-GUMED的子宫颈（CERVIX UTERI）组织样本的组织病理学图像。样本图像由奥林巴斯VS200切片扫描仪（20倍放大）拍摄，并保存为DICOM格式。患者、样本及诊断的详细信息如下：
患者：
年龄：49岁
临床描述：宫颈不典型增生（高级别鳞状上皮内病变，HSIL）
性别：女
诊断：
分类：ICD-10_10-20
分类代码：第十八章——症状、体征及其他未分类的异常临床与实验室检查结果
诊断：异常组织学发现
组织病理学检查结果：高级别不典型增生灶（HSIL/CIN III），位于转化区附近——免疫组化：p16+（块状反应），Ki67指数升高，累及上皮全层。不典型增生改变未累及宫颈管手术切缘。可见成熟及未成熟鳞状上皮化生特征，伴中度慢性炎症浸润。
样本：
材料：福尔马林固定石蜡包埋（FFPE）
采集方法：手术标本
部位：女性生殖器官
器官：子宫颈（CERVIX UTERI）
组织：宫颈外口
染色类型：阳性/苏木精-伊红（HE）
染色：不适用
抗体：不适用
技术：
设备：奥林巴斯VS200
镜头：20倍
机构：
来源：格但斯克医科大学