Expression data of miRNAs and mRNAs from the fetal rats with anorectal malformations

many dysregulated mRNAs as the primary factor could be play an important role in the development of anorectum we used microarrays to reveal the global programme of gene expression underlying the development of anorectal malformations. The fetal rats with anorectal malformations were successfully established, the terminal hindgut was collected for RNA extraction. This represents the microRNA component only.

诸多失调的信使RNA（mRNA）作为核心因素，可在肛管直肠发育过程中发挥重要作用。本研究通过基因芯片（microarray）技术，揭示了肛管直肠畸形发育背后的全局基因表达调控程序。我们成功构建了携有肛管直肠畸形的胎鼠模型，并收集其末端后肠组织进行RNA提取。本数据集仅包含微小RNA（microRNA）组分。