Oral health-related quality of life among pediatric liver transplant candidates

Abstract To assess the impact of oral conditions on the oral health-related quality of life (OHRQoL) of pediatric liver transplant candidates. This cross-sectional study included 60 children aged 13 to 48 months who were liver transplant candidates that attended the AC Camargo Cancer Center, São Paulo, Brazil. On the day of oral examinations, the children’s mothers were invited to answer two questionnaires; one related to children’s OHRQoL using the B-ECOHIS and another related to socioeconomic/demographic characteristics. Thereafter, a single, adequately trained dentist carried out children’s oral examinations for gingival inflammation (Silness-Löe index), dental plaque (Green-Vermillion Simplified index), dental caries (dmft index), developmental defects of enamel (DDE index), tooth discoloration, oral mucosal/lip alterations. The data collected also included socioeconomic/demographic characteristics and liver disease. The adjusted Poisson regression model was used to associate children’s socioeconomic/demographic characteristics and clinical conditions to the outcome. The adjusted regression model showed that children with untreated caries lesions (RR = 3.35, p

摘要 本研究旨在评估口腔状况对儿童肝移植候选者口腔健康相关生活质量（oral health-related quality of life, OHRQoL）的影响。本横断面研究纳入巴西圣保罗AC Camargo癌症中心就诊的60名年龄介于13至48个月的儿童肝移植候选者。在口腔检查当日，邀请患儿母亲填写两份问卷：其一采用B-ECOHIS量表评估患儿的OHRQoL，其二用于收集社会经济与人口学特征信息。随后，由一名经过充分培训的口腔科医师对患儿开展口腔检查，检测指标包括牙龈炎症（Silness-Löe index）、牙菌斑（Green-Vermillion Simplified index）、龋病（dmft index）、牙釉质发育缺陷（developmental defects of enamel, DDE index）、牙齿变色以及口腔黏膜/唇部病变。本次研究收集的数据还涵盖社会经济与人口学特征及肝脏疾病相关信息。本研究采用校正后的泊松回归模型，将患儿的社会经济与人口学特征、临床状况与研究结局进行关联分析。校正后的回归模型结果显示，存在未治疗龋损的患儿（相对风险RR=3.35，p