nuMoM2b Medications Used During Pregnancy [Drugs in Pregnancy] Dataset in Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be

Dataset contains the standardized and corrected medication data (i.e., standardized medication names, corrected misspellings, and corrected misclassifications found in the original data) along with the original section C01 data from the Medical Conditions and Medications form (VXX)
Study Description
NuMoM2b studied underlying, interrelated, mechanisms of adverse pregnancy outcomes (e.g., preterm birth, preeclampsia, fetal growth restriction) in pregnant women with no previous pregnancy lasting 20 weeks-0 days or more estimated gestational age (nulliparas). The network included 8 clinical sites, subsites, NICHD, and a data center. Women enrolled early in pregnancy and were followed through delivery, with study visits at 6 weeks-0 days to 13 weeks-6 days, 16 weeks-0 days to 21 weeks-6 days, 22 weeks-0 days to 29 weeks-6 days gestation, and delivery. Data collected through interviews, self-administered questionnaires, clinical measurements, ultrasounds, and medical records review included demographic, psychosocial, dietary, physiologic, health, and pregnancy outcome information. Subsets of participants enrolled in sleep disordered breathing, sleep patterns and quality, and fetal adrenal gland substudies. Pregnant women with no previous pregnancy lasting =20 weeks estimated gestational age (nulliparas); although 10,038 women enrolled in the study, during consent, only 9,289 of these women agreed to release their data into shared databases maintained by NIH

本数据集包含经标准化与校正的用药数据（即标准化用药名称、修正原始数据中的拼写错误与分类错误），以及来自医疗状况与用药表单（VXX）的原始C01区段数据。
研究概况
本研究为NuMoM2b研究，旨在探究既往无妊娠时长达到或超过20周0天（按估算胎龄计）的妊娠女性（初产妇，nulliparas）发生不良妊娠结局（如早产、子痫前期、胎儿生长受限）的潜在相互关联机制。该研究网络涵盖8个临床站点、分站点、美国国立儿童健康与人类发育研究所（NICHD）以及1个数据中心。研究对象于妊娠早期入组，并被随访至分娩，研究随访时点分别为妊娠6周0天至13周6天、16周0天至21周6天、22周0天至29周6天，以及分娩时。通过访谈、自填问卷、临床测量、超声检查与病历审查收集的数据，涵盖人口统计学特征、社会心理状况、饮食情况、生理指标、健康状况以及妊娠结局相关信息。部分研究对象参与了睡眠呼吸障碍、睡眠模式与睡眠质量，以及胎儿肾上腺相关亚研究。本研究的入组对象为既往无妊娠时长达到或超过20周（按估算胎龄计）的妊娠女性（初产妇，nulliparas）；尽管共有10038名女性入组本研究，但在知情同意阶段，其中仅9289名女性同意将其数据上传至由美国国立卫生研究院（NIH）维护的共享数据库中。